Mohammad Hassan Khan (মোহাম্মদ হাসান খান) is a Pakistani-American cricketer. He made his List A debut on 21 April 2016 for Sindh against Balochistan in the 2016 Pakistan Cup. Prior to his debut, he was named in Pakistan's squad for the 2016 Under-19 Cricket World Cup. He made his Twenty20 debut for Quetta Gladiators on 10 February 2017 in the 2017 Pakistan Super League. He made his first-class debut for Karachi Whites in the 2017–18 Quaid-e-Azam Trophy on 3 October 2017.

In December 2017, he was named as the captain of Pakistan's squad for the 2018 Under-19 Cricket World Cup. In April 2018, he was named in Khyber Pakhtunkhwa's squad for the 2018 Pakistan Cup. On 3 June 2018, he was selected to play for the Edmonton Royals in the players' draft for the inaugural edition of the Global T20 Canada tournament.